Past Awardee

Computational Design of Hepititis C Virus Vaccine Immunogens

Andrew Ferguson

College: Engineering
Award year: 2015-2016

Ferguson will work with NCSA's Innovatve Systems Laboratory to scale an algorithm for translating clinical sequences to viral fitness landscapes with the aim of providing transformational methods for the design of vaccines. The basic algorithm is a gradient descent method, and the computationally intensive part is the Monte Carlo evaluation of amino acid frequencies at each step of the iterative refinement.